Know about Childhood Cancer And Its Occurrence
When any teenager or a child is diagnosed with cancer, the child as well as his or her parents often wonder as to what they have done to get this life threatening disease, or if they have missed certain ways that might have prevented it. Despite an array of continuous clinical childhood cancer research since long, the truth remains, that it is still unclear and uncertain as to what precisely causes this disease among the kids.
Nevertheless, thanks to the research on this disease, what we have learnt so far is:
Mitosis (healthy cells divide). Differentiation (cells mature and learn their functions). Senescence (the cells age). Apoptosis/Necrosis (the cells die). These stages in the lifespan of a healthy cell are always controlled by many mechanisms inside the healthy cells and also by signals from the other cells that lies in its proximity. Together, these signals and mechanisms acts like a natural inner clock, which at the end determines the life span of the cells.
When this inner clock gets out of balance, cancer develops within our body. As the cell circle gets disturbed, and the inner clock is jeopardized, the cells starts mutating uncontrollably. Under this circumstance, the cells do not get the time to mature properly, which results in dysfunctional behavior of the healthy cells. As a result, healthy cells do not age properly and also they become unable to die.
There are several factors that can be responsible for this dysregulations within their cell-cycle and inside the cells. This is the reason as to why development of cancer is a multi-step and complex process. In several circumstances, the origin of this broken cell-cycle may lie in the change in the genetic make-up of these affected cells. The most common aberration under this circumstance happens when the genes carry incorrect information, which is known as Mutation, or the cell chromosomes has a missing or an addition genes which is known as Chromosome Aberration.
These subtle changes to the chromosomes and/or genes can ultimately result in lost function or impairment in proteins, which are usually accountable for regulating the cell-cycle that is required for proper signaling between cells and also for the repair of genetic damages.
So, a hereditary disposition for development of cancer at childhood has been described in association with rare birth defects that are characterized by certain wild and improper gene mutations.
But this must be remembered: Cancer is definitely neither a hereditary nor a contagious disease.
As children are not little adults. Research has shown that childhood cancer differ from cancer in the adults in several ways. So the type, frequency, possible causes and biological characteristics of childhood cancer are unique in their form.
While environmental factors, dietary and lifestyle play a major role in development of cancer in the adults, researches has shown, only a few risk factors such as a mother’s exposure to x-rays during her gravidity or an ionizing radiation has been identified as the risk factors in children. But these too, also account for a very small number of cases among children those who are affected with this life threatening disease.
Research on childhood cancer have shown evidences, that the primary few cells in various forms of childhood malignancies, such as Neuroblastomas, Wilms tumors, and in some of the brain tumors may already remain present at birth. This research on child cancer also reveals the fact that certain changes in the cells of the body may have already happed in the embryonic stage. Nevertheless, a more complete research is still needed as of date, to accurately describe what causes a specific cancer among the children.
Hence, to conclude it may be said, that there is no accurate scientific evidence that proves that childhood cancer can be a result of any specific human behavior.
Thus, the current state of knowledge does not determine that nor the parents neither the child has any proper reason to justify the cause for this disease.
Although many psychologists have propagated that psychological and emotional factors such as experiences of loss or troubled relationships within the family can be possible causes, but still these claims have not be proven scientifically true.